The National MALS Foundation is a nonprofit organization dedicated to the mission of providing education and support to those suffering from the debilitating symptoms of Median Arcuate Ligament Syndrome (MALS) and advocating to help raise awareness in the patient and clinical communities. As a foundation, we authored this chapter to help the medical community understand the patient and caregiver perspective through the diagnostic process, the surgical and treatment process, and finally the postsurgical process. We hope by providing the patient perspective in the MALS treatment journey, an understanding of the role patient advocacy and online support groups play, and the psychosocial impact MALS can have, we can help the medical community with a well-rounded view of patient support and outcomes.