6061 aluminum alloyAluminum alloy tends to formFe-bearing intermetallics Fe-bearing intermetallicsIntermetallic during the castingCasting process. These intermetallicsIntermetallic can hinder the remaining liquid from feeding, leading to severe solidificationSolidification shrinkage and hot tearingTearing defects. This study involves pouring molten Fe-containing 6061 aluminum alloyAluminum alloy into a V-shaped mold that can measure cooling curves at different positions. After solidificationSolidification, materials near the thermocouples are analyzed using electron microscopyElectron microscopy and synchrotron X-ray tomography to clarify the relationships among cooling curves, microstructureMicrostructure of intermetallicsIntermetallic, and porePore morphology. Furthermore, the cooling curve data and phase identification results are compared with kineticKinetics simulationsSimulation in CALPHADCALPHAD-based Pandat software. This study not only helps establish control standards for the composition, grain refinersGrain refiner, and cooling rateCooling rate of 6061 aluminum alloyAluminum alloy, but also serves as an application example of emerging analytical techniques such as 3D data visualization and integrated computational materials engineering.