Human considerations are central to the development of AI systems, especially in the context of agile safety planning. This chapter explores essential human aspects, such as situational awareness, controllability, and human oversight, which play a critical role in ensuring that high-risk AI systems operate safely and effectively. Through principles of human-centred design, the chapter also examines how interface design, agile development methods, and safety standards can support effective human–machine interaction. This understanding is essential for building AI systems that responsibly balance human involvement with automated processes in safety-critical environments.