Introduction

This chapter presents key considerations in the selection of antidepressant therapy, with a focus on SSRIs and SNRIs, which are widely used to treat major depressive disorder (MDD) and other psychiatric conditions. The text outlines essential factors for selecting the appropriate antidepressant, including individual symptom profiles, medical history, and potential side effects. Discussion includes onset of action, duration of treatment, potential drug interactions, and the risk of suicidality, particularly in younger populations. This introduction emphasizes a personalized treatment approach that balances efficacy, safety, and patient preferences to achieve optimal outcomes in antidepressant therapy.