Digital tomosynthesis (DTS) is an advanced X-ray technique that enhances soft tissue visualization by creating cross-sectional images from a series of projections. Originally developed to enhance the diagnostic accuracy of mammography, its applications have expanded into other clinical domains, including chest imaging. For pulmonary nodule biopsy, navigational bronchoscopy has incorporated DTS to provide updated imaging during the procedure that can mitigate “CT-to-body divergence,” which is thought to account for lower diagnostic yields in biopsy. Literature on bronchoscopic platforms utilizing DTS suggest a role for this imaging modality with potential expanded future use due to its lower radiation dose and cost.