The storage and preservation of edible mushrooms are critical aspects of ensuring their safety, quality, and nutritional value. This chapter explores various techniques and best practices aimed at prolonging the shelf life of mushrooms while preserving their freshness and flavor. Key considerations include proper handling to prevent contamination, optimal storage conditions such as temperature and humidity control, and the use of different preservation methods such as freezing, drying, pickling, and canning. Additionally, labeling, dating, and rotation practices play a crucial role in managing mushroom storage effectively and minimizing food waste. By adhering to safety guidelines and implementing proper preservation techniques, consumers can maximize the enjoyment and health benefits derived from mushrooms while reducing the risk of foodborne illness.