Green chemistry witnessed an enhanced development in making green catalysts by reducing the usage of toxic substances and harnessing renewable resources. Sustainable materials from bio sources, light sources, nano sources, and heteropolyacids act as green catalysts and exhibit potential candidates for synthesizing biomaterials for biomedical applications. This chapter highlights the use of various green catalysts in synthesizing biomaterials for biomedical purposes, including biosensors in clinical diagnosis, drug delivery, tissue engineering, wound healing, polymer coatings and inks for bioprinting. This chapter then discusses the methods involved in synthesizing green catalyst sources of green catalyst and finally concludes with future perspectives.