The research aims to determine the contribution of transport digitalization to improving the quality of life in Central Asia and develop recommendations for maximizing this contribution, using the Republic of Uzbekistan as an example. The authors conducted a correlation analysis to explore the relationship between government regulatory factors determining the digitalization of the transport and logistics sector and the quality of life indicators associated with this sector across all 12 Central Asian countries in 2023. The analysis reveals the advantages of transport digitalization for the quality of life in Central Asia. Government regulatory measures determining the digitalization of the transport and logistics sector are ranked by their significance for the quality of life in Central Asia. Additionally, a contradiction in the government regulation of transport and logistics digitalization in Uzbekistan is identified. The authors provide recommendations to resolve this contradiction and improve government regulation of transport and logistics digitalization in Uzbekistan. The main conclusion is that the digitalization of transport significantly improves the quality of life in Central Asian countries. The theoretical significance lies in clarifying the relationship between transport digitalization and quality of life in Central Asia. The importance of the proposed recommendations for economic policy is that they will enhance the effectiveness of government regulation of transport and logistics digitalization in Uzbekistan. The practical significance of the authors’ conclusions and recommendations is that they will improve the quality of life in Uzbekistan and other Central Asian countries.