This chapter examines how Alma Luz Villanueva’s Naked Ladies (1994) can be seen as a form of literary curanderismo (a traditional Mexican American holistic curative system) that works as a voice of prayer enabling healing, transformation, and rebirth for the protagonist and potentially a shift in reader awareness. The chapter dwells upon the depiction of the protagonist’s body as part of the consciousness and a source of natural, earthen, ancestral, and spiritual epistemologies realized through ritual engagement with nature, dream practice, and interaction with goddesses, to re-affirm the link to Indigenous traditions, thus placing the protagonist’s healing outside white patriarchal paradigms and Western binaries that rupture the self from the spiritual and from nature. The chapter demonstrates that Naked Ladies can be seen as decolonizing work as it reclaims ancestral and spiritual epistemologies and powerful feminine images that represent spiritual ways of knowing discredited by the imposition of the Western perspective emerging from colonization. Applying the curandera’s remedy to heal traumas caused by patriarchal and colonial systems, the protagonist’s self-growth is intrinsically linked to the realization of interconnectedness with the spiritual realm and the natural world, recognized as sites of ancestral knowledge that recreates the understanding of past and present traumas.