The rapid evolution of Artificial Intelligence (AI) has significantly transformed health care, particularly in the domain of Remote Patient Monitoring (RPM). This chapter explores the integration of AI in RPM, highlighting real-life applications, system architectures, and the benefits it brings to patient care and healthcare systems. Through an extensive analysis of current technologies, methodologies, and case studies, I present a detailed overview of how AI enhances monitoring accuracy, predictive analytics, and personalized treatment plans. The chapter also discusses the challenges and future directions in this field, providing a broad overview of AI’s role in revolutionizing remote patient care.