With the introduction of this handbook, we provide you—as readers, practitioners, and/or researchers—with a short overview on the history of innovation management and latest developments. It embeds the authors’ and interviewees’ contributions into a wider context, while at the same time providing you with guidance on the structure and thoughts behind the setup of this handbook. It starts with an overview of the development of innovation management from the first generation of innovation management until now, emphasizing factors that have influenced these developments. We further outline our understanding of holistic innovation, which we see as part of the 7th generation of innovation management, where we observe a movement from open to holistic innovation. In the end of the introduction, we outline the structure of this handbook and introduce the three main parts, i.e. innovation culture, strategic development, and sustainable change with chapters from our expert contributors.