Pile foundations continue to be one of the most preferred foundation alternatives for structures like high-rise buildings, tall chimneys, transmission line towers, offshore structures, etc., that are subjected to significant uplift forces. Predicting uplift capacity of pile foundation requires a thorough understanding of pile behaviour under uplift loads. Different analytical methods are available for estimating uplift capacity of single pile in which skin friction and soil’s shear strength are empirically correlated. In the present numerical investigation, a range of full-scale pile group models is analysed using a finite element program to investigate the response of pile groups subjected to pure uplift loading considering actual field condition. Soil is considered as elasto-plastic (Mohr–Coulomb model), whereas pile and pile cap are considered as linear elastic. Cylindrical concrete pile is taken, and variables considered include embedment length to diameter ratio (L/d), pile spacing, and number of piles in each group. Initially, a single pile model is validated with the results already published in the literature. From the results of the analysis, the load–displacement curves under vertical loading are used to evaluate group capacities, from which group efficiencies are calculated and compared with different L/d ratios and number of piles in group.