Cancer leads patients on a trajectory, including diagnosis, treatment, survivorship, and care through the balance of ones’ life. Each phase makes distinct demands on the patient, caregivers, healthcare providers, and complicated healthcare delivery systems. This chapter addresses survivorship care and the need for ongoing health maintenance from the perspective of the patient and their healthcare providers, including the vital role of navigation. The chapter will provide a broad description of the crosscutting issues surrounding cancer survivorship and will close with an example of survivorship care in practice.