Phantom Limb Pain (PLP) is a severe complication following limb loss, with limited effective treatment options. In an ongoing clinical trial, 35 individuals with limb loss completed 8 weeks of at-home Phantom Motor Execution (PME) therapy. Preliminary results indicate a significant improvement for various pain-related outcome measures with 57% of participants reporting a clinically significant treatment response. Using baseline pain measures and demographic factors, we achieve model predictions of treatment responders vs. non-responders with 78.6% accuracy. These findings highlight the potential of PME therapy as an effective treatment option for PLP management and seek to determine which patients are most likely to experience a clinically significant reduction in PLP. Identifying predictive factors that contribute to a successful response to PME therapy could enable more personalized and effective treatment plans.