The Features of Cortical Activation and Network Connectivity of Chronic Stroke in Response to Different Sensory Stimuli

This study aimed to explore the cortical activation and network connectivity in chronic stroke patients when exposed to various sensory stimuli. The subjects received three types of stimuli: robotic, NMES, and a combination of both. Near-infrared spectroscopy was employed to assess brain functional responses across various brain regions, such as the frontal lobe, premotor, sensory, motor, and somatosensory association. The findings indicated that stroke patients demonstrated diminished sensitivity to various sensory stimuli, primarily evidenced by the lack of significant distinctions in cortical activation and network connectivity in response to these stimuli. Furthermore, observations revealed notable variations in brain region regulation among stroke patients compared to the healthy control group, suggesting potential disruptions in the interregional regulatory mechanisms within the brains of stroke patients.