Water production of tight gas wells in LX block markedly hinders optimal gas extraction, compelling the urgent development of efficacious water control system. Current strategies include drainage gas production, mechanical water blocking, and chemical water blocking. Drainage gas extraction is suitable for gas wells with small water production. Mechanical water blocking is chiefly tailored for wells with well-defined water-producing layers. Chemical water blocking employs selective agents, such as polymers, microemulsions, and fuzzy-balls, to selectively control high-permeability layers and unlock the production potential latent within low-permeability reservoirs. Laboratory experiments evaluated the performance and injection volumes of the fuzzy-ball plugging system (FBPS), leading to three formulations for varied blocking strengths and the implementation of breakthrough pressure gradients (BPG) to assess control effect. The observed surge in water flow resistance (71.77%–78.92%) far exceeds gas resistance (13.34%–20.22%), maintaining stable gas and water control in tight gas wells. Fuzzy-balls degrade with a small percentage of ammonium persulfate, still offering water control properties. Field application of FBPS in wells LX-35 and LX D-1-1D significantly improved gas production and reduced water output. The FBPS’s adaptability for blocking in varied reservoir conditions, with potential for wide application due to its distinctive rheological properties and capability for selective, deep injection, positioning it as an effective solution for tight gas water control.