Temporal Bone Tumors, New Perspective in Systemic Treatment

Although exceptionally rare, the temporal bone structure presents an anatomic challenge to approaching temporal bone tumors. Squamous cell carcinoma accounts for a significant proportion of temporal bone tumors. Tumor formation in this anatomic region causes insidious symptoms such as tinnitus, vertigo, chronic pain, and hearing loss that can be attributed to a variety of other conditions. Computed tomography (CT) and magnetic resonance imaging (MRI) are used for diagnosis, while positron emission tomography-computed tomography (PET-CT) is used for metastatic disease. The modified Pittsburgh staging system is commonly used for staging. Treatment modalities vary according to presentation and patient preference. This chapter provides a comprehensive review of temporal bone anatomy, epidemiology, histology, and current treatment modalities.