Panuveitis with retinal vasculitis is the main form of ocular involvement in Behçet’s disease. The disease course is marked by sudden-onset uveitis attacks and clinical remission periods between attacks. Hypopyon iridocyclitis, diffuse vitritis, retinal infiltrates, and occlusive retinal periphlebitis may be seen during uveitis attacks. Fundus fluorescein angiography may show diffuse retinal capillary leakage during quiescent periods which indicates a high risk of recurrent uveitis attacks. Increased frequency and severity of uveitis attacks as well as incidence of complications such as cystoid macular edema and foveal ischemia are associated with poor visual outcome. Fundus fluorescein angiography is the gold standard in monitoring Behçet’s disease uveitis. Complete angiographic remission should be achieved by adequate therapy in order to preserve visual function. Biologic agents should be used in high-risk cases because of their proven superiority to conventional immunosuppressive agents in the treatment of Behçet’s disease uveitis.