Fluoride is a mineral which occurs naturally and often is ordinarily found in soil, rocks, and water. Fluoride may additionally enter water from other sources, including business operations, runoff from agriculture, and of course some natural events. Fluoride from such sources may disintegrate and find its way into ground water as well as surface water whenever precipitation or melting snow penetrates into the earth. It is called inevitable fluoride, which may be found in various amounts in a wide range of water supplies worldwide. Long-term excessive fluoride consumption has been scientifically connected to a number of physical problems, such as thyroid malfunction along with brain damage. Water poisoned with fluoride poses a serious risk to human health and necessitates extremely efficient water and environmental management. Fluoride poisoning is a serious health concern since fluoride is released into the environment by anthropogenic activities. The efficacy of fluoride removal is contingent upon chemicals in nature, topographical, and economic variables unique to each location; hence, actual applications may deviate from the theoretical framework. A process that satisfies requirements in one place could not meet those in another. Depending on the requirement, a public–private collaboration project should be carried out with sufficient preparation, oversight, and ongoing reinforcement.