Oral semisolid dosage forms for children are pharmaceutical formulations designed to administer medication in a convenient and easily ingestible form. These formulations are particularly beneficial for infants and young children who may have difficulty swallowing solid tablets or capsules. Semisolid formulations can be manufactured to provide good palatability by balancing their physical/mechanical properties, providing a pleasant taste and texture that children may find more enjoyable compared to traditional dosage forms. However, as some semisolid formulations can resemble regular candies, they may be tempting for children to consume in excess. This chapter provides an overview of semisolid oral formulations with many examples of research on suitable products. Overall, they offer improved palatability, accurate dosing, and ease of administration, ensuring that children receive their prescribed medication in a safe and effective manner.