Heavy metal (HM) contamination in soils has become a great concern because they lead to various environmental issues like detrimental to ecosystem stability, reduction in plant growth and development, and also harms human welfare. The HMs beyond the threshold level in soils can worsen the quality of soil and may even contaminate the food chain. In contrast to organic contaminants, heavy metals are non-biodegradable and have a propensity to accumulate in living things. There are some traditional methods (Physical and chemical methods) of remediation for heavy-metal contamination in soil are available but some drawbacks associated with these methods such as high cost, complicated, time-consuming, and non-sustainable. With the development of bioremediation technology, there is now an alternative to traditional methods for treatment of metal-contaminated soils. A technology called phytoremediation uses plants and microbes (called plant growth-promoting microbes (PGPMs)) to remove contamination from the soil, water, and air. Phytoremediation offers several advantages over the traditional approach such as low cost, eco-friendly, sustainable to the environment, etc. This chapter represents the use of phytoremediation and its mechanism for direct application in soils contaminated with heavy metals for promoting crop productivity.