To create universally welcoming spaces, many corporations have enforced policies that mandate inclusiveness regardless of age, race, sex, and, most controversial, sexual orientation/expression. Persons who support theological interpretations that condone anti-lesbian, gay, bisexual, transgender, queer, etc. (LGBTQ+) statutes struggle to adhere to diversity, equity, and inclusion (DEI) directives which require them to work alongside, or subordinate to, individuals whose way of life contradicts their religious beliefs. The purpose of this chapter is to highlight the obstacles faced by followers who are steadfast in their spiritual convictions, yet responsible for encouraging a diverse and inclusive work environment void of religious interference. Furthermore, it will expose how spirituality, if correctly intertwined, can support and advance DEI strategies within both corporate and faith-based sectors.