Dynamical identification can be a powerful tool in characterizing the behaviour of structures under dynamic excitation, as it allows for the validation of numerical models and for the assessment of structural integrity, highlighting potential flaws in the structural design or construction. In this respect, it is essential to ensure that the dynamic properties of the structure under consideration are accurately captured through calibration processes. The present study investigates the dynamic response of a real-scale building subjected to an electro-mechanical exciter through rigorous testing and numerical analyses. To this scope, a non-standardized vibrodyne exciter was first calibrated and then used to apply controlled vibrations to the real-scale building. The structural response was measured by means of acceleration transducers and compared with the numerical response obtained from a FEM model, with the aim of validation and refinement. By combining experimental testing with numerical analyses, the study contributes to improve the understanding of structural behavior under dynamic loading.