This chapter provides an overview of the current landscape of childhood chronic illness, including the academic, emotional, and social needs of children with chronic illnesses, an assessment of existing schooling options, and a discussion of areas for improvement in education to increase equitable experiences. Consistent challenges, such as chronic absenteeism, lack of teacher knowledge, and poor coordination of healthcare and educational services, are identified as barriers to success. Suggestions are provided to improve equity of experience, such as developing support programs to complement reintegration (academic), providing more comprehensive group learning opportunities for children in treatment (emotional), utilizing technology to encourage the continuation of social relationships (social), and shifting attitudinal views toward chronic illness (overall acceptance). UNESCO’s framework for ensuring equity and the Key Educational Factors (KEF) for promoting the educational success of children with chronic illnesses are offered as tools to help develop and assess programs. Finally, the need to center children’s voices in research and practice is emphasized to further the overall understanding of chronic illnesses, to foster the development of a culture of childhood chronic illness, and to decrease discrimination.