While advancements in surgical techniques and perioperative care have certainly improved outcomes, gastric resection, especially when accompained by lymph node dissection still carries significant risks, particularly for frail patients. Infectious complications are among the concerns as surgical procedures can compromise the body’s natural defenses and increase susceptibility to infections. Factors such as the extent of the surgery, the patient’s overall health status, and the presence of other medical conditions can all influence the likelihood of developing complications. Pneumonia and intra-abdominal abscess are adverse events that not only lead to prolonged hospital stays but can also have significant implications for the overall treatment plan and patient outcomes. Delayed administration of adjuvant chemotherapy due to postoperative complications can compromise the effectiveness of the treatment regimen and potentially impact long-term survival rates. Additionally, the postoperative inflammatory response, exacerbated by infectious complications, can further complicate recovery and increase the risk of other adverse events. Prevention strategies play a crucial role in minimizing the incidence of infectious complications. This may include meticulous surgical techniques to reduce the risk of contamination, prophylactic antibiotics, and comprehensive perioperative care protocols aimed at optimizing patient health before, during, and after surgery.