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Although Type 1 Diabetes (T1D) represents only around 10% of total cases of diabetes worldwide, it imposes a substantial economic impact on healthcare systems and, particularly, on patients’ quality of life. People with T1D must control their blood glucose (BG) levels 24 h a day, 365 days a year. With the advent of Continuous Glucose Monitoring (CGM), research turned over the design of a system that can automatically regulate the BG concentration and reduce the number of health-related decisions a person with T1D needs to undertake daily. Today, several Automated Insulin Delivery (AID) systems are cleared for clinical use, and their adoption is rapidly increasing. This chapter introduces the fundamental BG control problem in T1D and discusses the underlying challenges, opportunities, existing solutions, and available tools to evaluate AID-related control system designs.

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On a Benchmark Problem for Automated Insulin Delivery in Type 1 Diabetes

  • 章节

  • 发表日期：

    2025年

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  • Vihangkumar V. Naik,
  • Clara Escorihuela-Altaba,
  • Jose Garcia-Tirado

摘要

Although Type 1 Diabetes (T1D) represents only around 10% of total cases of diabetes worldwide, it imposes a substantial economic impact on healthcare systems and, particularly, on patients’ quality of life. People with T1D must control their blood glucose (BG) levels 24 h a day, 365 days a year. With the advent of Continuous Glucose Monitoring (CGM), research turned over the design of a system that can automatically regulate the BG concentration and reduce the number of health-related decisions a person with T1D needs to undertake daily. Today, several Automated Insulin Delivery (AID) systems are cleared for clinical use, and their adoption is rapidly increasing. This chapter introduces the fundamental BG control problem in T1D and discusses the underlying challenges, opportunities, existing solutions, and available tools to evaluate AID-related control system designs.