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Targeted Supportive Therapy with Coenzyme Q10 in Clinical Practice

  • Anna Gvozdjáková,
  • Plácido Navas,
  • Guillermo López Lluch

摘要

Coenzyme Q10 (CoQ10) has a key role in the generation of energy for cells, its deficiency is associated with the development of many diseases, including mitochondrial. Targeted, supportive therapy with CoQ10 regenerates the health of mitochondria, contributes to improving the health of patients, contributes to the reduction of oxidative stress, and improves the quality of life of patients. Despite the number of published works on the beneficial effect of CoQ10 during the past 66 years, many unanswered questions remain about the mechanisms of action of CoQ10. It is not known the exact mechanism of passage of CoQ10 through the blood–brain barrier, the mechanism of transport of CoQ10 to target cells, whether it will be possible to inject CoQ10 intravenously to patients, why supplementation with CoQ10 was not successful in some clinical studies. ChatGpt answers two questions about CoQ10. Clarification of the mentioned problems requires additional studies.