Biocompatible Structured Materials for Tissue Engineering Based on Ethylene–Vinyl Acetate Copolymers: From Controllable Waviness and Microroughness to Spatially Modulated Electrostatics and Diffusion Programmable by Electron Beam Modifications
摘要
The article begins with a comprehensive review of the topic of EVA-containing polymer composites for tissue engineering on ethylene–vinyl acetate copolymer-based systems. The article focuses on the problem of textural and (bio)chemical biocompatibility of the material. As a solution to the first problem, it is proposed to use electron microscopy and correlation-spectral image analysis, which emulates laser diffraction (2D FFT implemented with the FFTW library in QAVIS software). The article also describes the modernization and digitization of an electron microscope, thanks to which such analysis becomes possible in a video stream and in real time or post factum. Also eleven tables of analysis results are given so that each specialist in the field of cell biology and regenerative medicine can independently assess the suitability of certain polymer compositions with different ratios of components for his tasks.