Malaysia has long been plagued by the issue of a lack of organ donors in the population. Government and non- government institutions have made numerous attempts to address this issue, but it has not yet been fully solved. The research found that most respondents were less interested in organ donation efforts, but they were in favor of continuing the efforts in order to educate Muslims about the value of organ donation. Although the Quran and Hadith, do not clearly specify that organ donation is permitted in Islam. In 1970, with the modern advancement in medicine the National Fatwa Councils has finalized the decision to permit the organs and tissues donation for transplantation and it is in fact a must. The objective of this study is to design a PSA (Public Social Announcement) to investigate how much the Muslim community in Malaysia has accepted this fact and aware the significance of the organ donation campaign. The research methodology identified the ADDIE model with questionnaire to the target audience to conclude its findings. The research objectives include promoting knowledge and understanding of organ donation among Malaysian Muslims, developing a 2D animation PSA, and evaluating its effectiveness in raising awareness. The results conclude an increasing knowledge among Malaysian Muslims to participate in organ donation. The finding shows that 83.9% strongly agree that the PSA is effective to spread awareness on the organ donation campaigns. The unique feature of Augmented Reality sets this 2D PSA to engage with the storyline and information. That said, this PSA contributes the understanding of animated PSA on significance society related to health, attitudes and behaviors within cultural and religious groups, advancing health communication strategies to the nation.