Immunological Defense Mechanisms of the Respiratory System

This chapter comprehensively explores the intricate immunological defense mechanisms in the respiratory system. We delve into the orchestrated interplay of innate and adaptive immunity to counteract airborne pathogens, pollutants, allergens, etc. Key elements such as mucosal immunological defenses, lung mucosa-resident immune cells (i.e., macrophages, dendritic cells, plasma cells, innate lymphoid cells (ILC), natural killer (NK) cells, and T lymphocytes), and humoral responses are described in detail. Understanding these robust defense mechanisms is vital not only for shedding light on respiratory health but also for advancing strategies in therapeutic interventions and vaccine development.