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Upper Respiratory Tract Involvement in Cystic Fibrosis: Clinics and Diagnosis

  • Pelin Asfuroğlu,
  • Larry C. Lands

摘要

Cystic fibrosis (CF) is an autosomal recessive genetic disease caused by mutations in the cystic fibrosis transmembrane conductivity regulator (CFTR) gene. Mutations in CFTR result in viscous mucus that impairs mucociliary clearance in both the upper and lower airways. Upper respiratory tract involvement is common in CF.