As globalization has expanded international trade, so has the range of criminal activities broadened and diversified. By their very nature, security issues such as transnational organised crime (TOC) are a challenge for many nations. Issues such as piracy, terrorism, trafficking in illicit drugs, human beings and arms, threatens necessary infrastructure, are interconnected and transcend boundaries. In particular, drug, human trafficking, piracy and cyber-crime are activities of organized crime groups, generating enormous profits. The wide range of criminal activities are inter-related to some extent, and have a potential impact on the success derived through their contributions to security, stability and safety. The main aim of this paper is to raise awareness of the nature of transnational organised crimes and their consequences on a regional, national and international level. It is an essential prerequisite for designing appropriate responses, to exploring, building and strengthening sustainable directions in policy recommendations, law enforcement, healthcare and criminal justice systems that will enable the institutions more effectively to prevent, investigate and combat transnational related crimes in the future. Furthermore, the purpose of this research is to examine existing literature on TOC and demonstrate that the development of Information and Communication Technology (ICT) and globalisation has led to the expansion and complexity of criminal organisations that take advantage of these changes for financial gain. The study considers many types of Transnational Organised Crime across Africa and elucidates on cybercrime, a particularly prevalent form of TOC internationally and in Nigeria in the twenty-first century. Several aspects of the cybercrime perpetrator's social learning process, information-sharing practices, and group dynamics are revealed. It concludes that transnational crime cannot be effectively addressed from a national standpoint; rather, a concerted international and regional effort is required in order to enhance the fragile capacities of states, subregions, and regional organisations.