Pharmaceutical Applications of Peptides Formulated in Biocomposite Nanomaterials

Short amino acid chains known as peptides are widely used in pharmaceutical applicationsPharmaceutical applications due to their exclusive therapeutic potential and distinct biological activities. These peptides are utilized as therapeutic agentsTherapeutic agent for the treatment of various medical conditions and diseases, peptide hormones for hormone deficiency treatment, peptide vaccines to be utilized as antigens to induce specific immune responses against cancer cells or pathogens, and peptide-based drug delivery systemsDrug delivery system. However, poor stability, limited oral bioavailabilityBioavailability, high immunogenicity leading to reduced efficacy, high cost of production, low target specificity, challenges in formulation and tissue penetration. Recently, nanomaterials, especially nanocomposites, have been utilized for the formulation of therapeutic peptides to improve their efficiency and overcome their limitations. In particular, biocomposite nanomaterials from natural sources are also reported to effectively formulate and deliver therapeutic peptides toward target site. Thus, this chapter is an overview of various biocomposite nanomaterials for the formulation of peptides to improve their efficiency. Additionally, pharmaceutical applicationsPharmaceutical applications of these biocomposite nanomaterial formulated peptides were also discussed.