This chapter explores the intersection of spirituality and technology, framing spirituality as a universal theory that integrates mind–body wellness, consciousness, and mindfulness. Through the lens of Spiritual Artificial Intelligence (AI), we trace the evolutionary journey of spirituality and intelligence, emphasizing key milestones. The study also examines Spiritual Wellness, a core aspect of the wheel of wellness, and the integration of Intelligence Quotient (IQ) and Emotional Quotient (EQ) as Spiritual Quotient (SQ). Finally, the emerging need to quantify spirituality using AI is discussed, along with the potential implications of Spiritual AI.