Bioneurodesign™ is an innovative interdisciplinary field combining biodesign, neuroscience, and systemic design thinking to foster human-centric innovation. This study employs a six-stage methodology encompassing identification, speculation, observation, implementation, acceleration, and expansion to create designs aligned with human neurological responses and sustainable practices. Using advanced artificial intelligence, this approach personalizes and enhances the design process. The findings highlight the potential of this methodology to transform design practices, enhance human well-being, and promote environmental sustainability. Key results include enhanced user experience through neuro-responsive design elements and sustainable product lifecycles, paving the way for responsible innovation in diverse applications. The study demonstrates that integrating neurofeedback and AI-driven personalization in the design process can lead to more effective and user-centric products. Furthermore, the commitment to ecological integrity through sustainable materials and practices underscores the dual focus on human and environmental health, making this framework a comprehensive approach for future design innovations. This interdisciplinary approach promises significant advancements in various fields, including healthcare, architecture, and consumer electronics, by creating products that are not only functional but also emotionally and cognitively resonant with users.