Behcet’s Disease

Behcet’s disease (BD) is a systemic, inflammatory disease of unknown etiology. Onset is typically in young adults manifesting with recurrent oral aphthous ulcers, genital ulcers, and uveitis. Patients with BD may also concurrently exhibit multi-organ involvement including vascular, neurological, and gastrointestinal manifestations. The etiology of BD is thought to be auto-immune in nature with possible triggers including infectious, environmental, or genetic etiologies. BD occurs most frequently in Eurasian populations extending from eastern Asia to the Mediterranean basin. Vascular complications can uniquely affect small, medium, and large blood vessels. The diversity of the clinical presentations of BD requires consultation from various medical specialists with treatments centered upon symptoms and the degree and severity of the disease.