Posttraumatic growth refers to the positive changes that individuals may experience after facing a traumatic event. Childhood cancer can be considered a potentially traumatic event since it is a life-threatening disease that can shake the assumptions of both children and caregivers. This chapter discusses posttraumatic growth in the context of childhood cancer, including the relationship between posttraumatic growth and posttraumatic stress symptoms, and the cognitive processing involved in PTG for both children and caregivers. Additionally, it highlights the main measures used to assess PTG in children and caregivers, as well as the main intervention techniques used to promote posttraumatic growth.