The World is jumping to the next phase of the Transportation System with rapid development of the Internet of Things (IoT) and Intelligent Transportation System. IoT is the most significant technological advancement allowing smart devices and vehicles to communicate with each other and capable of exchanging information with each other. The Scenario mentioned above, will generate so much data that the ability to handle it appropriately is the foundation of Smart Transportation System and to carry out this action we have two best technologies as of now which are Cloud Database Management System (CDBMS) and Blockchain Technology (BT). In this chapter we explore the Benefits, Challenges and Synergies of CDBMS and Blockchain in Smart Transportation System. The enormous amount of data generated by the Smart Transportation Network requires the technology that is Scalable, Flexible and Efficient which is achieved by CDBMS and Decentralized, Transparent and Secure which is fulfilled by BT. This is particularly true for the pivotal plots, which involve several parties and sensitive data, such as Financial Transactions, owner’s information and Vehicles Identification. User’s and Service Providers trust is increased because of the Immutable nature of BT, which guarantees that all transactions and data exchanges are Verifiable and Tamper-proof. Moreover, this chapter also projected over to New Developments and Future Enhancements such as using Edge Computing to reduce Latency and role of AI for the Optimized Transportation Networks. This seeks to give Researchers, Practitioners, and Policymakers involved in the creation and implementation of Smart Transportation System useful insights by giving a thorough overview of the current state of Affairs, Technological developments, and implementation techniques. In conclusion, we can justify that the combination of CDBMS and BT stick with notable promise for the enhancement of Reliability, Security and Efficiency of the Smart Transportation System. But in order to realize a genuine Integrated and Intelligent Transportation environment, these benefits can only be realized by tackling innate difficulties and encouraging collaboration among diverse stakeholders.