This research emphasises the critical role of Enterprise Resource Planning (ERP) systems in ensuring the survival of organisations while acknowledging the difficulties in implementing them. The study proposes using Interpretive Structural Modeling (ISM) to identify the interdependencies among the crucial success factors and Matrice d'Impacts Croisés Multiplication Appliqués à un Classement (MICMAC) analysis to determine their driving and dependence powers. The data was collected through the focal group approach involving experts and company representatives. The ISM model revealed the hierarchical relationships among the factors, while the MICMAC classified them into four clusters. The study highlights the specific challenges that manufacturing companies in Brazil face, and it emphasises the importance of overcoming these obstacles by cultivating a technological culture and combining human skills with technology to implement ERP projects successfully.