Given the rapid evolution of the industry and the increasing demands for adaptation and digitalization, it becomes imperative for companies to be prepared for these changes by integrating various technologies and driving changes across different areas of the organization. Understanding the level of readiness is crucial for making informed decisions and ensuring a successful transition to the new industrial paradigm. To this end, this study aimed to analyze how two multinational industries prioritize factors for Industry 4.0 readiness in their strategic planning. To reach this goal, the level of their readiness for Industry 4.0 was measured. The research revealed that large corporations predominantly achieved readiness levels of 4 and 5 on a scale of 1–5 concerning the size of the companies. This underscores the importance of a corporate culture that values innovation, employee training, and a robust strategy for embracing the challenges and opportunities presented by Industry 4.0.