The objective of this study is to examine the environmental impacts generated during the construction and end-of-life phases of a concrete reinforced wainscoting building. The modelling is performed by using GaBi software and the professional database of this software. CML 2001 method is used to evaluate the im-pacts. The functional unit is defined as “Usable living area”. The investigated environmental impact categories can be listed as: Global Warming (GWP), Abiotic Depletion/fossil (ADPf), Eutrophication (EP), Human Toxicity (HTP), Acidification (AP), Photo-chemical Ozone Creation (POCP), Freshwater Aquatic (FAETP) and Terrestrial Eco-toxicity (TETP) potentials. The system boundaries for the study are defined as the construction and demolition stages. Scenarios dealing with alternative usage of insulation materials (rock wool and Expanded Polystyrene, EPS) are established. Elevations in ADPf and POCP with a lowered TETP are observed in case of using EPS instead of rock wool. Although no substantial effects are obtained for other environmental impact categories due to the mentioned change of EPS usage. The scenarios involving the end-of-life phase indicate that recycling of metal such as steel, secondary usage of PVC windows and glasses, and a part of the wood, substantially lowers ADPf, AP, EP, FAETP, GWP, HTP, and POCP impact categories. The findings of this study will serve as a guide to decision makers.