Neuroimmunology of Endometriosis-Associated Pain and Its Psychological Aspects

EndometriosisEndometriosis-associated painPain (EAP) is a major health concern in women of reproductive age. Due to the limited knowledge in the etiology and mechanisms of EAP, current treatmentTreatment options remain deficient. In this chapter, we review the potential mechanisms contributing to EAP in the roles of neuroinflammationNeuroinflammation, neurogenesis and neural sensitization, as well as current clinical and pre-clinical treatmentsTreatment for EAP. Also the current knowledge and interrelationship between EAP and psychological well-being for the EAP treatmentTreatment are discussed. Potential of individualized, multisubject care, integrating medical and psychological management for EAP are appraised.