The main question of this paper is related to whether and in what way we understand the notion of topological deformability, which appears in numerous texts of architectural theory from the beginning of the 1990s until today. In general, the paper deals with the problem of the denotation of concepts from other scientific fields, and shows how the architectural discourse changes the meaning of a mathematical concept, determining it within its own discipline. The transition of the term topological deformability is set as an example of how architecture uses and improves its inherent interdisciplinary dimension, as well as an example of how the way we research in architecture could make a tangible social impact. The first part of this paper will focus on introducing and analyzing the concept of topological deformability and its transition from mathematics to architectural theory. In the second part, it will examine how, through different theoretical approaches, the term topological deformability influences the transformation of the thinking modality in architecture, and how it traces the narrow path through architectures’ knowledge toward the wider audience. Therefore, architecture’s dominant as an instrument of plural social reality will be emphasized. The research will show how the term topological deformability through architecture opened the way to changing the idea of otherness, leading to the essential acceptance of differences.