The construction industry is facing significant challenges in aligning with the circular economy principles, primarily due to the management of Construction and Demolition waste. Effectively addressing this issue is pivotal in minimizing the environmental impact of buildings at the end of their life cycle. An essential step towards this goal involves establishing a robust supply chain for the recovery and reuse of waste materials and avoiding those to be landfilled. In this research a literature review has been carried out to map and analyse the existing challenges which prevent the establishment/implementation of a recovery route for the facade materials and components. These challenges could be transformed in actionable opportunities to tackle the problem. The facade systems are characterised by a relatively short service life compared to other building layers, and they undergo frequent process of refurbishment and renovation. The result is a large waste stream associated with the facades layer. Several issues were found to have consequences among multiple categories, showing the complexity of the End-of-Life (EoL) stages of facade materials. The identified challenges and opportunities in the EoL scenario of the facades can be categorised into technical, economic, logistical, legislative, and cultural domains. Finally, the paper discusses ongoing trends and research stream in the field of facades and building sustainability, such as the benefits of the design for disassembly approach in creating systems and components with a higher recovery potential and the design for reuse/recovery of materials.