The policy to mitigate climate change necessarily passes through the reduction of the carbon footprint of the construction sector, responsible for 40% of global emissions. With the aim of encouraging circular economy processes, the methodology developed considers a quantitative/qualitative approach aimed at optimising the benefits of applying module ‘D’ of the LCA Building, with reference to the UNI EN 15978 standard. The case study concerns the design of an urban regeneration intervention, in the city of Cordoba, Argentina, consisting of an aggregative system of modular typologies, with a steel structure. Concerning the quantitative thresholds, the disassembly incidences were considered, applying the most restrictive parameter among the international sustainability protocols, including the Italian CAM. As far as qualitative parameters are concerned, the PROGRESS (Provision for Greater Reuse of Steel Structures) method was applied, a tool developed to evaluate the reuse of structural steel components. The validation of the method involves the development of an improvement hypothesis using existing, decommissioned steel components, highlighting both the economic benefits and the environmental impact of the process, through the application of the A1-A3 Building LCA module.