Intrathecal baclofen (ITB) therapy is a good therapeutic, evidence-based option and effective treatment for spasticity in children with cerebral palsy. It has also been used in children with dystonic cerebral palsy. ITB results in decreased spasticity, with the lower extremities more relieved than the upper extremities, fewer spasms, improvement in ankle clonus, increased range of motion, and improved ambulation in children with spastic diplegia. As well, ITB therapy can help in reducing contractures, improving functional abilities, and facilitating patient care by parents and caregivers. ITB therapy involves the surgical implantation of a programmable pump in the abdomen with a thin catheter tracking to the spinal subarachnoid space for the release of baclofen into the cerebrospinal fluid. There can be surgical complications as well as complications related to the patient’s medical condition, the hardware implanted, and the medication. Despite this, the overall perceptions of ITB therapy have been found to be positive with most parents or caregivers satisfied and willing to go through the process again if needed for their child.(AUThe keyword “Extra-axial hemorrhage” is not found in the text. Please check and confirm if this keyword can be removed from the index.)(AUThe keyword “Familial spastic paraplegias (FSPs)” is not found in the text. Please check and confirm if this keyword can be removed from the index.)(AUThe keyword “Galveston fixation” is not found in the text. Please check and confirm if this keyword can be removed from the index.)(AUThe keyword “Investigational New Drug (IND) application” is not found in the text. Please check and confirm if this keyword can be removed from the index.)

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Intrathecal Baclofen Therapy

  • Michael Vassilyadi

摘要

Intrathecal baclofen (ITB) therapy is a good therapeutic, evidence-based option and effective treatment for spasticity in children with cerebral palsy. It has also been used in children with dystonic cerebral palsy. ITB results in decreased spasticity, with the lower extremities more relieved than the upper extremities, fewer spasms, improvement in ankle clonus, increased range of motion, and improved ambulation in children with spastic diplegia. As well, ITB therapy can help in reducing contractures, improving functional abilities, and facilitating patient care by parents and caregivers. ITB therapy involves the surgical implantation of a programmable pump in the abdomen with a thin catheter tracking to the spinal subarachnoid space for the release of baclofen into the cerebrospinal fluid. There can be surgical complications as well as complications related to the patient’s medical condition, the hardware implanted, and the medication. Despite this, the overall perceptions of ITB therapy have been found to be positive with most parents or caregivers satisfied and willing to go through the process again if needed for their child.(AUThe keyword “Extra-axial hemorrhage” is not found in the text. Please check and confirm if this keyword can be removed from the index.)(AUThe keyword “Familial spastic paraplegias (FSPs)” is not found in the text. Please check and confirm if this keyword can be removed from the index.)(AUThe keyword “Galveston fixation” is not found in the text. Please check and confirm if this keyword can be removed from the index.)(AUThe keyword “Investigational New Drug (IND) application” is not found in the text. Please check and confirm if this keyword can be removed from the index.)