The aim of this work is to present models of digital technology utilization in the complex world of universities to activate face-to-face and distance teaching and learning projects. Academic training can no longer be conducted locally without considering the global context that digital technologies have consolidated as the reality in which twenty-first century individuals operate and interact. Today, the common challenge for universities worldwide is how to best adapt to the digital society and create integrated and open teaching and learning systems within the context of a globalized economy. The transformation of universities is no longer a choice but an indispensable necessity. New generations of students cannot do without using the Internet to follow courses and develop knowledge and skills. This essay aims to present concrete models of how traditional and digital universities have been able to reinvent themselves by creating new international alliances to establish a global network of universities on the internet. These universities combine their knowledge, share curricula, and create digital content in dedicated learning environments designed with new psychopedagogical theories appropriate to technological evolution. The organizational models of digital universities are also structured to truly respond to the challenges and needs of a globalized and interconnected society.