The adoption of Artificial Intelligence (AI) within the realms of project and portfolio enterprise management (PPEM) is revolutionizing the domain of project management. AI's potential to boost efficiency, productivity, and decision-making marks a significant shift, necessitating a new set of skills and competencies for project management practitioners. This ushers in an era marked by enhanced capabilities and novel challenges. With AI automating routine operations and offering insights based on data, it's imperative for project management professionals to adapt and evolve to maintain their critical role in this AI-influenced epoch. This study delineates five essential success factor dimensions essential for project management professionals to excel in this evolving landscape. These include deep industry knowledge, proficiency in core project portfolio enterprise management (PPEM) processes, fundamental coding skills, expertise in data visualization, and proficiency in data science. Developing these competencies enables project management professionals to not only excel in the era of AI but also play a pivotal role in shaping the future of project portfolio management.