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Metabolites Treasure from Endophytes: Advances, Applications and Technological Challenges

  • Murad Muhammad,
  • Sani Begum,
  • Allah Ditta,
  • Yong-Hong Liu,
  • Li Li,
  • Wen-Jun Li

摘要

Endophytes, microorganisms found in plant tissues, have been found to contain a wealth of unique compounds with vast potential. This chapter delves further into the wide variety of metabolites produced by endophytes and highlights their value to the pharmaceutical, agricultural, and biotechnology sectors. This chapter describes the state-of-the-art tools and techniques used to isolate, characterize, and synthesize metabolites derived from endophytes, illuminating the novel advances in exploiting their bioactive qualities. It also explores the difficulties of production process optimization, expansion, and maintaining stable metabolite outputs. Case studies and applied uses of endophyte-derived metabolites in the real world demonstrate their importance in medication research, disease control, and agricultural improvement. The chapter also discusses the challenges and restrictions provided by regulatory frameworks and sustainability worries in using these precious assets. Overall, this chapter provides an in-depth review of what is currently known about metabolites derived from endophytes, stressing their immense promise and the technological obstacles researchers face. In the ever-changing world of biotechnology and natural product discovery, understanding and overcoming these obstacles will be crucial to releasing the full potential of endophyte-derived metabolites for use in a wide range of sectors and fields.