Hyper-realistic avatars (HRAs) are digital embodiments of a human, created by capturing and combining that person’s video and vocal likenesses. We study the efficacy of videos delivered by HRAs as a communication channel in business-to-business applications as compared to videos delivered by their human counterparts. An online experiment with 290 participants gathered performance and biometric data across three video treatments. There are no statistically significant differences in information retention, engagement, or trust between respondents who watched the real human versus the HRA. A significant (p = 0.003) positive difference is found in information retention between the HRA-delivered video and the video delivered by the HRA with disclosure. This study lays the foundation for future HRA research directions.